KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC6
All Species:
23.64
Human Site:
S626
Identified Species:
47.27
UniProt:
Q96SB8
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96SB8
NP_001135758.1
1091
126326
S626
V
A
R
A
V
M
Q
S
Q
K
P
P
K
N
C
Chimpanzee
Pan troglodytes
XP_001136387
1091
126280
S626
V
A
R
A
V
M
Q
S
Q
K
P
P
K
N
C
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532882
1606
180795
S1141
V
A
R
A
V
M
Q
S
Q
K
P
P
K
N
C
Cat
Felis silvestris
Mouse
Mus musculus
Q924W5
1097
127179
S632
V
A
R
A
V
M
Q
S
Q
K
P
P
K
N
C
Rat
Rattus norvegicus
NP_001101484
1097
127259
S632
V
A
R
A
V
M
Q
S
Q
K
P
P
K
N
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505822
579
67328
R145
E
E
E
S
R
N
M
R
Y
N
Q
K
L
L
D
Chicken
Gallus gallus
XP_419962
1096
127736
S633
K
A
R
E
V
M
Q
S
N
N
P
P
K
N
C
Frog
Xenopus laevis
Q6P9I7
1128
130494
K664
E
A
R
E
I
M
Q
K
R
A
P
P
R
N
C
Zebra Danio
Brachydanio rerio
NP_001121806
1090
126266
S629
D
A
R
R
V
M
Q
S
K
G
G
Q
A
P
R
Tiger Blowfish
Takifugu rubipres
Q802R8
1090
124790
G632
E
A
R
R
V
M
Q
G
R
N
P
P
Q
N
C
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794820
1236
142110
N736
I
L
K
D
I
M
N
N
L
I
P
Q
H
A
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12749
1114
127990
R651
E
A
R
N
F
L
Q
R
N
P
V
N
V
N
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
N.A.
63.3
N.A.
90
90.4
N.A.
38.1
59.7
60.5
51.4
45.9
N.A.
N.A.
N.A.
30.2
Protein Similarity:
100
100
N.A.
66.1
N.A.
96.3
96.2
N.A.
44
77.9
76.7
70.3
67
N.A.
N.A.
N.A.
50.9
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
0
73.3
53.3
40
60
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
6.6
73.3
73.3
46.6
73.3
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
84
0
42
0
0
0
0
0
9
0
0
9
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
67
% C
% Asp:
9
0
0
9
0
0
0
0
0
0
0
0
0
0
9
% D
% Glu:
34
9
9
17
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
9
0
9
9
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
9
0
0
0
17
0
0
0
0
9
0
0
0
0
0
% I
% Lys:
9
0
9
0
0
0
0
9
9
42
0
9
50
0
0
% K
% Leu:
0
9
0
0
0
9
0
0
9
0
0
0
9
9
0
% L
% Met:
0
0
0
0
0
84
9
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
9
0
9
9
9
17
25
0
9
0
75
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
9
75
67
0
9
0
% P
% Gln:
0
0
0
0
0
0
84
0
42
0
9
17
9
0
0
% Q
% Arg:
0
0
84
17
9
0
0
17
17
0
0
0
9
0
9
% R
% Ser:
0
0
0
9
0
0
0
59
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% T
% Val:
42
0
0
0
67
0
0
0
0
0
9
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _